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 Cancer involves the misregulation of cell growth, proliferation, differentiation and death programs. These programs are all regulated at the gene expression level, and chromatin structures and modifications are fundamental regulators of these programs. Indeed, the regulation of many of the most important oncogenes and tumor suppressors operate either largely or in part through a chromatin regulatory mechanism. Furthermore, chromosomal instability and DNA hypomethylation are found in a majority of cancers. Here, one must understand both how these processes normally work and precisely how they are misregulated in cancer in order to design effective and targeted therapies. The 2012 Keystone Symposia meeting on Chromatin Dynamics aims to understand the mechanistic relationships between chromatin and transcription as well as between chromatin and DNA repair and stability, processes at the heart of cancer initiation, prevention, and treatment. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Epigenomics, which will share a keynote address and two plenary sessions with this meeting.

 每年一届　

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 2.单项服务的费用以最终确认单为准.
 3.参会整体流程服务费1000人民币/人.
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