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 Emerging themes from several traditionally disparate areas of research have begun to coalesce around the concept that the complex microbial communities that inhabit most external human surfaces play a key role in health and disease. Specifically, processes including basic immune system development, host-pathogen interactions, metabolic disease and cancer are all greatly influenced by the composition and bioactivity of the microbiota that live within us. Understanding how mammalian hosts regulate their microbiota and the myriad of ways by which the microbiota can alter susceptibility to a wide range of diseases is a key opportunity to better understand numerous diseases and, subsequently, provide strategies to promote human health. Thus, the goal of the Keystone Symposia meeting on The Microbiome is to facilitate the understanding of mechanisms that maintain a healthy host-microbiota relationship and explore how perturbations in this relationship increase susceptibility to a variety of diseases, especially those associated with chronic inflammation. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Innate Immunity: Sensing the Microbes and Damage Signals, which will share a keynote address and three plenary sessions with this meeting.

新兴的主题从几个传统截然不同的研究领域已经开始联合周围的概念,使复杂的微生物群落,大多数人类居住外部表面中发挥关键作用,在健康和疾病。具体地说,流程,包括基础免疫系统的开发,病原体宿主代谢疾病和癌症的相互作用,都极大地影响了的成分和生物活性的微生物活在我们身上了。了解哺乳动物和微生物主机调节他们的无数的方式可以改变对微生物广泛的疾病是一个关键的机会更好地理解众多疾患,后来,提供策略,促进人类健康。所以,目标的学术会议重点在于促进肠道菌群的理解病原体宿主机制,保持一个健康良好的关系,探索如何在这样的关系中,增加扰动对各种疾病,特别是伴随着慢性炎症。跨学科的互动的机会将会显著地提高并行会议上由天然免疫:感觉微生物和损伤信号,这将共享一种主题演讲和三次全会上的这个会议。

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