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Stem cell studies have demonstrated unexpected plasticity of cellular differentiation programs and challenged the long-standing paradigm of progressive irreversibility of cell fate during development. The field of stem cell biology interfaces with many areas of basic biology including developmental biology, tissue growth and homeostasis, regeneration, cancer and aging. Unlike most meetings on stem cells, the Keystone Symposia meeting on The Life of a Stem Cell: From Birth to Death focuses on stem cells within the context of the organism. Stem cell systems are discussed with respect to the life cycle of whole organisms: gametogenesis and embryogenesis, where tissue types are established; maturity, where organ systems are maintained in homeostasis; and aging, where stem cells systems change physiologically or because of disease. Speakers have been chosen to broadly reflect lessons learned from a variety of model organisms, experimental approaches and organ systems. ¸Éϸ°ûÑо¿ÒѾ֤Ã÷ÁËϸ°û·Ö»¯µÄ·½°¸ÒâÏë²»µ½µÄ¿ÉËÜÐÔºÍÌôÕ½£¬ÔÚ·¢Õ¹¹ý³ÌÖеÄϸ°ûÃüÔ˵ij¤ÆڵĽ¥½ø²»¿ÉÄæתµÄ·¶Ê½¡£¸Éϸ°ûÉúÎïѧÓë·¢ÓýÉúÎïѧ£¬×éÖ¯Éú³¤ºÍ¶¯Ì¬Æ½ºâ£¬ÔÙÉú£¬°©Ö¢ºÍË¥ÀϵĻù±¾ÉúÎïѧµÄÐí¶àÁìÓò£¬°üÀ¨½Ó¿ÚÁìÓò¡£²»Í¬µÄ¸Éϸ°û£¬Ò»¸ö¸Éϸ°ûµÄÉúÃüµÄ»ùʯ£¬×¨ÌâÌÖÂÛ»á»áÒéµÄ´ó²¿·Ö»áÒ飺´Ó³öÉúµ½ËÀÍöµÄÖصãÔÚ¸Éϸ°ûµÄÓлúÌåÖС£¸Éϸ°ûϵͳÊÇÓëÕû¸öÉúÎïÌåµÄÉúÃüÖÜÆÚÌÖÂÛ£ºÅä×ÓºÍÅßÌ¥·¢Óý£¬×éÖ¯ÀàÐÍ£¬½¨Á¢³ÉÊ죬Æ÷¹Ùϵͳ±£³Ö¶¯Ì¬Æ½ºâ;ºÍÀÏ»¯£¬ÆäÖиÉϸ°ûϵͳ£¬»òÒò¼²²¡£¬ÉúÀí¸Ä±ä¡£Ñ¡ÔñÑïÉùÆ÷Òѹ㷺µØ·´Ó³´Ó¸÷ÖÖģʽÉúÎʵÑé·½·¨ºÍÆ÷¹ÙϵͳµÄ¾Ñé½Ìѵ¡£ |
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