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This meeting will focus on recent advances in viral immunity and host gene influence that have most excited the scientific community. Systems biology approaches are being increasingly applied to the exploration of host-pathogen interactions, including the impact of viral infection on innate and adaptive immunity. Accordingly, the keynote talk will be on this topic. The first full session on the next day will focus on innate immunity, a field that continues to evolve rapidly and hold great interest in the field. In the evening the audience will hear from others who have successfully applied a systems biology approach to examine virus-host interactions. The second day explores adaptive immunity, a topic that historically has been a centerpiece for this meeting, and an area that continues to move forward rapidly. On the third day, the morning session will focus on immune evasion and subversion and will illustrate how formidable the opposition can be and why vaccine development for a number of important human diseases is so challenging. Talks on persistent and chronic viral infections, a topic with clear relevance to a number of human diseases, will be covered in the evening session. The morning session of the final day will cover immune tailoring in non-lymphoid tissues; talks will illustrate how different host responses can and must be, depending upon anatomical location of the infection. The final session will cover the latest advances in the development of vaccines and therapeutics, the traditional ending for this meeting series and a reminder to attendees of the ultimate objectives. Overall, the objective of the Keystone Symposia meeting on Viral Immunity and Host Gene Influence is to accelerate progress in understanding and manipulating anti-viral immunity to improve human health. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on HIV Vaccines, which will share a keynote address and three plenary sessions with this meeting. We anticipate this pairing will facilitate a wider cross-fertilization of ideas and foster innovative collaborations among scientists working in vaccinology and those studying innate immune mechanisms and other viral diseases. ±¾´Î»áÒ齫רעÓÚÔÚ²¡¶¾ÃâÒߺÍËÞÖ÷»ùÒòµÄÓ°Ï죬×îÐ˷ܵĿÆÑ§½çµÄ×îнøÕ¹¡£ÏµÍ³ÉúÎïѧµÄ·½·¨£¬ÕýÔÚÔ½À´Ô½¶àµØÓ¦ÓÃÓÚËÞÖ÷ - ²¡ÔÌåÏ໥×÷ÓõÄ̽Ë÷£¬°üÀ¨²¡¶¾¸ÐȾÏÈÌìÃâÒߺÍÊÊÓ¦ÐÔÃâÒßµÄÓ°Ïì¡£Òò´Ë£¬Ö÷Ö¼Ñݽ²½«ÔÚ´ËÖ÷Ìâ¡£µÚÒ»µÚ¶þÌì»áÒ齫²àÖØÓÚÏÈÌìÃâÒßϵͳ£¬Ò»¸öÁìÓò¼ÌÐøÑ¸ËÙ·¢Õ¹²¢±£³ÖÔÚ¸ÃÁìÓòµÄ¼«´óÐËȤ¡£ÔÚÍíÉϵĹÛÖÚ»áÌýµ½´ÓÄÇЩÒѾ³É¹¦µØÓ¦ÓÃϵͳÉúÎïѧµÄ·½·¨Ñо¿²¡¶¾ - ËÞÖ÷Ï໥×÷ÓᣵڶþÌì̽ÌÖÊÊÓ¦ÐÔÃâÒߣ¬ÀúÊ·ÉÏÒ»Ö±ÊDZ¾´Î»áÒéµÄºËÐÄÖ÷Ì⣬²¢¼ÌÐøÏòǰ·¢Õ¹Ñ¸ËÙµÄÇøÓò¡£µÚÈýÌ죬ÉÏÎçµÄ»áÒ齫֨µã·ÅÔÚÃâÒßÌӱܺ͵߸²£¬²¢ËµÃ÷ÈçºÎÇ¿´óµÄ·´¶ÔÅÉ£¬¿ÉÎªÊ²Ã´Ò»Ð©ÖØÒªµÄÈËÀ༲²¡ÒßÃçµÄ·¢Õ¹ÊǺÜÓÐÌôÕ½ÐÔ¡£³Ö¾ÃÐÔºÍÂýÐÔ²¡¶¾¸ÐȾ£¬Ò»Ð©ÈËÀ༲²¡µÄÏà¹ØÐÔÓÐÃ÷È·µÄÖ÷Ì⣬»á̸½«Éæ¼°ÔÚÍíÉϵĻáÒé¡£×îºóÒ»ÌìÉÏÎçµÄ»áÒ齫ÌÖÂÛÔÚ·ÇÁܰÍ×éÖ¯µÄÃâÒß¼ô²Ã;»á̸½«ËµÃ÷²»Í¬µÄËÞÖ÷·´Ó¦ÈçºÎ£¬±ØÐëÈ¡¾öÓÚ¸ÐȾµÄ½âÆÊλÖá£×îºóÒ»´Î»áÒ齫°üÀ¨ÔÚÒßÃçºÍÁÆ·¨£¬¶Ô±¾´Î»áÒéϵÁеĴ«Í³½áÊøµÄ·¢Õ¹µÄ×îнøÕ¹£¬²¢ÌáÐÑÓë»áÕßµÄ×îÖÕÄ¿±ê¡£×ܵÄÀ´Ëµ£¬ÌÝÐβ¡¶¾ÃâÒߺÍËÞÖ÷»ùÒòµÄÓ°ÏìרÌâÌÖÂÛ»á»áÒéµÄÄ¿µÄÊǼÓËÙ£¬ÔÚÀí½âºÍ²Ù×÷¿¹²¡¶¾µÄÃâÒßÁ¦£¬¸ÄÉÆÈËÀཡ¿µ·½ÃæÈ¡µÃ½øÕ¹¡£¿çѧ¿ÆµÄ»¥¶¯»ú»á²¢·¢»áÒéÉϰ¬×̲¡¶¾ÒßÃ罫´ó´óÔöÇ¿£¬Õ⽫Óë±¾´Î»áÒé·¢±íרÌâÑÝ˵ºÍÈý´ÎÈ«Ìå»áÒé¡£ÎÒÃÇÔ¤¼ÆÕâÖÖÅä¶Ô£¬½«ÓÐÖúÓÚÒ»¸ö¸ü¹ã·ºµÄ˼Ïë½»Á÷ºÍ´Ù½øÔÚÒßÃçºÍÑо¿ÏÈÌìÃâÒß»úÖÆ¼°ÆäËü²¡¶¾ÐÔ¼²²¡¹¤×÷µÄ¿ÆÑ§¼ÒÖ®¼äµÄ´´ÐºÏ×÷¡£ |
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