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 Inflammation is inextricably woven into the natural history of atherosclerosis. The macrophage is integral to the pathogenesis of atherosclerosis, functioning at the intersection of inflammation and cholesterol homeostasis, making its biological properties an important topic. Consequently, macrophage biology will be a major focus of the Keystone Symposia meeting on Molecular Basis of Vascular Inflammation and Atherosclerosis. The critical contributions of innate and adaptive immunities to atherosclerosis will also be reviewed, and a session on fundamental features of the inflammatory process, including its resolution, will introduce concepts likely to influence future paradigms in the atherosclerosis field. Recently discovered factors that regulate levels of atherogenic lipoproteins, key initiators of arterial inflammation, will be presented. Other highlights include progress in genomic approaches to discover risk factors for coronary artery disease, as well as advances in imaging techniques to detect atherosclerotic plaques, cellular composition of plaques and trafficking of immune cells in vivo. The keynote address will highlight emerging roles of nuclear hormone receptors as integrators of plaque lipid metabolism and immune activity.

炎症是动脉粥样硬化的自然历史有着千丝万缕织成。巨噬细胞是动脉粥样硬化的发病机制的组成部分，在炎症和胆固醇平衡运作，其生物学特性的一个重要课题。因此，巨噬细胞生物学的主要焦点将是一个梯形专题讨论会会议上的血管炎和动脉粥样硬化的分子基础的。有先天免疫和适应性的豁免权动脉粥样硬化的重要贡献，也将进行审查，对炎症过程中的基本特征，包括其第的会议，将引进在动脉粥样硬化领域可能影响到未来的范式概念。最近发现的因素，调节动脉粥样硬化的脂蛋白的水平，动脉炎的关键发起人，将提交。其他精彩节目包括基因方法的进展，发现冠状动脉疾病的危险因素，以及在成像技术的进步来检测动脉粥样硬化斑块，斑块和贩卖体内的免疫细胞的细胞组成。主题演讲将突出集成斑块脂质代谢和免疫活性的核激素受体的新兴角色。

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