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 Fibrosis is a pathological process in which diseased tissue is replaced with excess extracellular matrix ultimately leading to organ scarring and failure, a final common pathway in many forms of chronic disease affecting multiple tissues. Currently, there are minimal and inadequate treatment options for fibrotic disease. The field of fibrosis is emerging and there is a strong need to understand the cellular, molecular and genetic basis of fibrosis in humans and to develop animal models that reproduce and dissect this pathological process. There is also a need to identify prognostic markers of disease susceptibility, biomarkers of disease progression and improved technologies to monitor the effectiveness of new therapies. The goal of the Keystone Symposia meeting on Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics is to bring together researchers and clinicians in academia and industry to provide an integrated perspective of basic disease mechanisms, the more pragmatic challenges associated with executing clinical trials and approaches to improve clinical development of anti-fibrotic drugs.

纤维化是一种病理过程，在过剩细胞外基质，最终导致器官的疤痕和失败，最终在许多慢性疾病的影响多种组织形式的共同通路取代病变组织。目前，有纤维化疾病的很少，不足的治疗方案。纤维化的领域是新兴的，有强烈的需要了解在人类肝纤维化的细胞，分子和遗传基础和发展的动物模型，复制和剖析这一病理过程。还有一个需要，以确定疾病的易感性的预后指标，生物标志物来监测疾病的进展和改进的技术新疗法的有效性。梯形的专题讨论会会议上纤维化：基础研究对人类疾病和新型疗法翻译的目标是汇集学术界和工业界的研究人员和临床医生的基本发病机制提供了一个综合的角度，更加务实的挑战与执行临床试验和方法，以提高抗肝纤维化药物的临床开发。

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 3.参会整体流程服务费1000人民币/人.
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